No, it is not required.
For Arria® 10 EMIF IP, it is not necessary to set the I/O Standard in the Assignment Edition, but rather in the "FPGA I/O" tab of the EMIF IP Parameter Editor.
This setting is reflected in the EMIF IP file and the setting is applied at compile time.
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Category: External Memory Interface
Tools: Quartus® Prime
Device: Arria® 10